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目的 预防中晚期大肠癌手术后的肝转移。方法 对70例Dukes’B、C期大肠癌根治术后门静脉插管永久皮下置泵化疗与外周静脉化疗组的前瞻性研究。结果 泵疗组的肝转移5/35例,腹膜复发8/35例;对照组分别为12/35例和7/35例。结论 门脉泵化疗对预防肝转移有意义,使用方便。
Objective To prevent liver metastasis after surgery for advanced colorectal cancer. Methods A prospective study of 70 patients with Dukes’ B and C colorectal cancer after radical resection of the portal vein was performed with permanent subcutaneous pump chemotherapy and peripheral intravenous chemotherapy. Results Hepatic metastasis in the pump group was 5/35 cases, and 8/35 cases of peritoneal recurrence. The control group was 12/35 cases and 7/35 cases respectively. Conclusion Portal pump chemotherapy is very effective in preventing liver metastasis and is easy to use.