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目的探讨丙泊酚复合瑞芬太尼用于人工流产手术的麻醉效果及安全性。方法:60例ASAⅠ-Ⅱ级自愿接受人工流产术的患者,随机分为丙泊酚复合瑞芬太尼组(R组)和丙泊酚复合芬太尼组(F组),每组30例。R组静注瑞芬太尼1μg/kg,F组静注芬太尼1μg/kg,30秒钟后均静注丙泊酚2mg/kg。待患者睫毛反射消失后开始手术。记录麻醉效果满意率,患者的意识恢复时间、定向力恢复时间、离院时间和不良反应的发生情况。结果两组病例麻醉效果均满意,生理参数之间相比较无显著性差异(P>0.05),但R组的意识力恢复时间、定向力恢复时间、离院时间明显短于F组(P<0.01)。结论丙泊酚复合瑞芬太尼或芬太尼均可为人工流产手术提供较好的麻醉和镇痛效果,但瑞芬太尼停止输注后作用消退时间比芬太尼快,苏醒迅速,并发症少,更有利于病人的早期恢复,但须加强呼吸的监测和管理。
Objective To investigate the anesthetic effect and safety of propofol combined with remifentanil in induced abortion. Methods: Sixty ASA Ⅰ-Ⅱ patients undergoing voluntary abortion were randomly divided into propofol combined remifentanil group (R group) and propofol combined fentanyl group (F group), with 30 patients in each group . Group R received intravenous remifentanil 1μg / kg, group F received fentanyl 1μg / kg, and intravenous infusion of propofol 2mg / kg after 30 seconds. After the eyelash reflex disappeared, the patient started surgery. The satisfaction rate of anesthesia, the recovery time of consciousness, the recovery time of orientation force, the time of leaving hospital and the occurrence of adverse reactions were recorded. Results The anesthetic effect was satisfactory in both groups, but there was no significant difference in physiological parameters between the two groups (P> 0.05). However, the recovery time, recovery time and departure time were significantly shorter in group R than those in group F (P < 0.01). Conclusions Both propofol and remifentanil or fentanyl can provide better anesthetic and analgesic effects for induced abortion. However, the effect of remifentanil after stopping infusion is faster than that of fentanyl, rapid recovery, Less complications, more conducive to the early recovery of patients, but to strengthen respiratory monitoring and management.