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内皮祖细胞(endothelial progenitor cells,EPCs)是内皮细胞的前体细胞。Asahara等[1]于1997年首先从外周血中分离出CD34+/VEGFR2+的血管EPCs,它具有向内皮细胞分化的潜能。研究结果表明,EPCs是一群主要来源于胚胎发育阶段的中胚层和出生后的骨髓、主要存在于胎肝和脐带血以及成人骨髓和外周循环血中的、能够分化为内皮细胞的多潜能细胞[2]。EPCs不仅参与人胚胎血管发生,而且参
Endothelial progenitor cells (EPCs) are the precursors of endothelial cells. Asahara et al [1] first isolated blood vessel EPCs of CD34 + / VEGFR2 + from peripheral blood in 1997, which has the potential to differentiate into endothelial cells. The results show that EPCs are a group of mesodermal and postnatal bone marrow mainly derived from the embryonic developmental stage and are mainly pluripotent cells capable of differentiating into endothelial cells in fetal liver and umbilical cord blood, adult bone marrow and peripheral blood [ 2]. EPCs not only involved in human embryonic angiogenesis, but also reference