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目的分析南平市疑似预防接种异常反应(AEFI)的发生特征,评价监测系统的运转情况及预防接种的安全性。方法用描述性流行病学方法对监测资料进行分析。结果 2008—2012年共报告AEFI 570例,发生率为9.1/10万,主要为一般反应535例(93.9%)、异常反应32例(5.6%)和偶合症3例(0.5%);报告时间以11~12月最多,年龄以<1岁最多(41.2%);发生率较高的疫苗为全细胞百白破(171.9/10万)、白破二联(61.43/10万)和无细胞百白破(34.9/10万)。结论南平市AEFI监测具有一定的敏感性。
Objective To analyze the occurrence characteristics of suspected immunization anaphylaxis (AEFI) in Nanping City, evaluate the operation of monitoring system and the safety of vaccination. Methods Descriptive epidemiological methods were used to analyze surveillance data. Results A total of 570 AEFI cases were reported from 2008 to 2012, with a prevalence of 9.1 / 100,000. Among them, 535 cases (93.9%) were general reactions, 32 cases (5.6%) were abnormal reactions and 3 cases (0.5%) were coupled diseases. The highest incidence was in the age of 1 year (41.2%) in the period from November to December, and the highest incidence of the vaccine was total cell diphtheriae (171.9 / 100000), white diphtheria (61.43 / 100000) and cell free Baibab broken (34.9 / 100,000). Conclusion Nanping AEFI monitoring has a certain sensitivity.