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超抗原是一种强大的T细胞激活剂,金黄色葡萄球菌肠毒素A(SEA)是由葡萄球菌产生的一种外毒素,为目前研究最广泛的一种超抗原,也是唯一进入癌症治疗临床试验的超抗原。介绍了SEA在抗癌药物中的应用及其研究进展。
Superantigen is a powerful T cell activator. Staphylococcus aureus enterotoxin A (SEA) is an exotoxin produced by staphylococci. It is the most widely studied superantigen and the only one that enters the cancer treatment clinic Experimental superantigen. The application of SEA in anticancer drugs and its research progress are introduced.