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应用益气活血法,静滴参麦注射液及丹参注射液治疗47例慢性肺心病低氧血症患者,并以同期具有可比性的25例非益气活血法治疗的患者作对照。临床结果表明,益气活血法能显著提高PaO_2、SaO_2及2、3-DPG水平,从而起到改善肺心病低氧血症的作用;同时,结合血液流变学及免疫等指标的变化,初步认为其作用机理可能与改善肺通气功能、降低血粘度、调整通气/血流比例及提高机体的防御作用等因素有关。
Forty-seven patients with chronic cor pulmonale and hypoxemia were treated with Yiqi Huoxue Decoction, intravenous Shenmai Injection and Salvia Miltiorrhiza injections, and compared with 25 patients treated with non-Yiqihuoxue therapy in the same period. The clinical results show that the method of benefiting qi and activating blood circulation can significantly improve the levels of PaO_2, SaO_2 and 2,3-DPG, thereby improving the hypoxemia of pulmonary heart disease. At the same time, combined with the changes of hemorheology and immune index, The mechanism of action may be related to the improvement of pulmonary ventilation, lowering of blood viscosity, adjusting the ratio of ventilation / blood flow and enhancing the body’s defensive effects.