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喹胺酸是我国药物学家1975年研制的治疗金属中毒的络合剂。我们于10年前曾试用于轻度慢性铅中毒及铅吸收各3例。治前留尿两天的尿铅为66-119ug/d,平均97ug/d。3例隔日肌肉注射喹胺酸0.25g/d,注射日尿铅261—680ug/d,平均497ug/d,相当于治疗前的5.1倍;3例隔日肌注0.5g/d(分两次注射),注射日尿铅230-1,110ug/d平均60ug/d,相当于疗前的6.2倍,从尿中证明它有一定的驱铅作用。但作用不强,6例中3例先用喹胺酸0.5g/d共四天,第1注射日尿铅分别为663、1,110、700ug;喹胺酸治疗结束后隔一天再分别注射0.5g/d的Na-DMS、Ca-EDTA或Ca-DTPA,该注射日的尿铅为774、2,940、2,920ug
Quinic acid is a Chinese medicine pharmacologist developed in 1975 for the treatment of metal poisoning complexing agent. Ten years ago, we tried three cases of mild chronic lead poisoning and lead absorption. Pre-treatment urine urinary lead for two days was 66-119ug / d, an average of 97ug / d. 3 cases of intramuscular injection of quetiapine 0.25g / d, injection of lead urinary lead 261-680ug / d, an average of 497ug / d, equivalent to 5.1 times before treatment; 3 cases intramuscular injection of 0.5g / d ), Injection of lead urinary lead 230-1, 110ug / d average 60ug / d, equivalent to 6.2 times before treatment, from the urine to prove that it has some anti-lead role. But the effect is not strong, 6 cases in 3 cases first with quinoline 0.5g / d for a total of four days, the first day of injection of lead were 663,1,110,700ug; quinoline acid were injected one day after the other day 0.5g / d of Na-DMS, Ca-EDTA or Ca-DTPA, the date of the injection of lead for the 774,2,940,2,920ug