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198 6年Ｍｏｓｍａｎｎ等[1] 首次提出鼠的辅助性Ｔ细胞 (Ｔｈ)可分为Ｔｈ1和Ｔｈ2细胞 ,1991年Ｍａｇｇｉｅ等[2 ] 发现人的Ｔｈ细胞与鼠相似 ,也可分为Ｔｈ1和Ｔｈ2两型。Ｔｈ1主要分泌干扰素 γ (ｉｎｔｅｒｆｅｒｏｎ γ ,ＩＦＮ γ)、白细胞介素 2 (ＩＬ 2 )及淋巴毒素
198 6 Mosmann et al [1] first proposed that murine helper T cells (Th) can be divided into Th1 and Th2 cells. In 1991, Maggie et al. [2] found that human Th cells are similar to mice and can also be divided into Th1 and Th2 Two types. Th1 mainly secretes interferon γ (IFN γ), interleukin 2 (IL 2) and lymphotoxin