支气管哮喘是一种以慢性气道炎症为特征的异质性疾病,具有喘息、气促、胸闷和咳嗽等呼吸道症状病史,伴有可变的呼气气流受限,呼吸道症状和强度可随时间而变化[1]。哮喘的病因有多种,包括遗传、感染、环境、肥胖等。哮喘与呼吸道感染密切相关,病毒、非典型病原体感染引起哮喘急性发作在多年的临床研究中已被证实,而细菌定植感染与哮喘的关系尚不明确[2]。本 Bronchial asthma is a heterogeneous disease characterized by chronic airway inflammation with a history of respiratory symptoms such as wheezing, shortness of breath, chest tightness and coughing, with variable expiratory airflow limitation, respiratory symptoms and intensity over time The change [1]. There are many causes of asthma, including heredity, infection, environment, obesity and so on. Asthma and respiratory infections are closely related to the virus, atypical pathogens caused by acute exacerbation of asthma in many years of clinical studies have been confirmed, and the relationship between bacterial colonization and asthma is not clear [2]. this