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作者用高分辨线阵型实时超声波扫描器(Aloka250)及放免法测定血清 AFP 值,对157例经组织学证实为肝硬化的无症状病人进行了检查。初筛时超声波发现13例病人有肝脏病灶存在,其中10例证实为肝细胞癌,1例为血管瘤,2例属于灶性脂肪变。首次 AFP 测定如下:109例 AFP 值<20ng/ml,46例 AFP值在20～400ng/ml 之间,3例 AFP>400ng/ml。在10例肝细胞癌中,3例 AFP 值<20ng/ml,4例 AFP 在20～400ng/ml 之间,3例AFP>400ng/ml。随访期间又诊断5例肝癌,在6个月时发现2例,18个月发现1例,最后
The authors used a high-resolution linear real-time ultrasound scanner (Aloka 250) and radioimmunoassay to measure serum AFP values, and examined 157 asymptomatic patients who were histologically proven to be cirrhotic. At the time of primary screening, 13 patients with liver lesions were found to be present, 10 of which were hepatocellular carcinoma, 1 of which was hemangiomas, and 2 of which were focal fatty changes. The first AFP measurements were as follows: 109 AFP values <20 ng/ml, 46 AFP values between 20 and 400 ng/ml, and 3 AFP> 400 ng/ml. Among the 10 hepatocellular carcinomas, 3 had AFP values of <20 ng/ml, 4 had AFPs of 20 to 400 ng/ml, and 3 had AFPs of >400 ng/ml. During the follow-up period, 5 cases of liver cancer were diagnosed. Two cases were found at 6 months, and 1 case was found at 18 months.