论文部分内容阅读
目的 探讨我国经济发达地区乙肝疫苗接种的最佳免疫策略。方法 以北京市东城区防疫站 1991～ 1998年乙肝疫苗免疫接种及乙肝发病、死亡资料及费用调查为基础 ,对新生儿高剂量的免疫策略进行成本效益分析。结果 1991年对全部新生儿实施预防接种 ,投入疫苗接种成本 34 2 4万元 ,因免疫接种而避免急、慢性乙肝及肝癌而节省费用 5 91 79万元 ,可获 4 99 2万元的净效益 (NB) ,效益成本比 (BCR)为 15 5 8。结论 现行免疫接种方案经济效益显著 ,建议经济发达地区仍实行高剂量免疫策略。
Objective To explore the best immunization strategy of hepatitis B vaccination in economically developed areas in China. Methods Based on the investigation of hepatitis B vaccine immunization, hepatitis B incidence, death data and cost in Dongcheng District Epidemic Prevention Station of Beijing from 1991 to 1998, the cost-benefit analysis of high dose immunization strategy in neonates was carried out. Results In 1991, all newborns were vaccinated, the cost of vaccination was 342.4 million yuan, the cost of avoiding acute and chronic hepatitis B and liver cancer by immunization was 591.79 million yuan, and the net income was 49.2 million yuan Benefit (NB), cost effectiveness ratio (BCR) of 15 5 8. Conclusion The current immunization programs have significant economic benefits and suggest that high-dose immunization strategies should still be implemented in economically developed areas.