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目的分析危重症患者的镇痛镇静治疗效果。方法纳入54例危重症患者,对其采取镇痛镇静治疗措施,用咪唑安定、丙泊酚和芬太尼静脉推注以及静脉内持续泵入,并根据镇痛镇静的结果对泵入的剂量进行合理调节。观察患者呼吸参数和循环参数在镇痛镇静治疗前后(包括治疗前,治疗后1 h,治疗后12 h和治疗后24 h)的变化。结果经过治疗,镇静镇痛效果良好,患者呼吸参数和循环参数均明显改善,其中,用药前、用药后1 h、用药后12 h、用药后24 h这4个时间段中,RR分别为(23.81±7.71)、(17.24±6.89)、(17.48±5.32)、(18.12±4.31);PIP分别为(27.32±6.92)、(25.21±6.39)、(23.09±5.21)、(22.45±5.10);Pa O2分别为(103.53±30.32)、(111.24±26.89)、(115.48±26.71)、(118.15±25.96);Sp O2分别为(92.48±3.71)、(98.21±2.39)、(98.09±2.50)、(98.92±2.58);HR分别为(109.45±20.34)、(99.23±18.23)、(98.34±18.21)、(95.14±17.21);MAP分别(85.42±15.23)、(79.44±13.45)、(83.46±16.23)、(83.01±15.22);CVP分别为(13.46±3.42)、(11.45±2.56)、(11.09±2.50)、(11.02±2.11),跟治疗前对比差异均有统计学意义(P<0.05)。结论危重症患者的镇痛镇静治疗非常重要,其有利于缓解患者疼痛情况和焦虑烦躁症状,改善临床生命体征,提高抢救成功率,值得推广。
Objective To analyze the analgesic and sedative effect of critically ill patients. Methods Fifty-four critically ill patients were enrolled in this study. The patients were treated with sedation and analgesia. The patients were treated with intravenous injection of midazolam, propofol and fentanyl, and continuous intravenous infusion. According to the results of analgesia and sedation, Make reasonable adjustments. The changes of respiratory parameters and circulatory parameters in patients before and after sedation (including treatment before treatment, 1 h after treatment, 12 h after treatment and 24 h after treatment) were observed. Results After treatment, the sedative and analgesic effect was good, and respiratory parameters and circulatory parameters of patients were significantly improved. Among the four time periods before treatment, 1 h after treatment, 12 h after treatment and 24 h after treatment, the RRs were ( PIP were (27.32 ± 6.92), (25.21 ± 6.39), (23.09 ± 5.21) and (22.45 ± 5.10), respectively; PIP was (27.32 ± 6.92), (25.21 ± 7.7), (17.24 ± 6.89), (17.48 ± 5.32) and PaO2 were (103.53 ± 30.32), (111.24 ± 26.89), (115.48 ± 26.71) and (118.15 ± 25.96), respectively; Sp O2 were (92.48 ± 3.71), (98.21 ± 2.39) and (98.09 ± 2.50) (98.92 ± 2.58), HR were (109.45 ± 20.34), (99.23 ± 18.23), (98.34 ± 18.21), (95.14 ± 17.21), MAP were (85.42 ± 15.23), (79.44 ± 13.45), (83.46 ± (P <0.05). The mean CVP were (13.46 ± 3.42), (11.45 ± 2.56), (11.09 ± 2.50) and (11.02 ± 2.11) respectively, with statistical significance ). Conclusion The sedation and sedation treatment of critically ill patients is very important. It is beneficial to relieve pain and anxiety and irritability, improve clinical vital signs and improve the success rate of rescue.