一般人认为氟化物引起的鼻粘膜损害是非特异性的。Eoliam 和 Eramian 二氏检查了从事铅生产并暴露在氟化物环境中的工人,发现鼻粘膜有慢性卡他性炎症,肥大和瘢痕化改变。Golusinski 氏等检查了铝厂工人,发现6%有鼻粘膜腐蚀;工人中呈现鼻粘膜肥大性改变者较萎缩性改变多见,这些作者 Most people think that fluoride-induced nasal mucosal damage is nonspecific. Eoliam and Eramian II examined workers engaged in lead production and exposure to fluoride and found that nasal mucosa had chronic catarrhal inflammation, hypertrophy and scarring. Golusinski et al. Inspected aluminum foundry workers and found that 6% had nasal mucosal erosion; workers who presented changes in nasal mucosal hypertrophy were more common than atrophic changes. These authors