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目的 研究西比灵治疗脑出血周围水肿的疗效 ,进一步探讨西比灵的作用机制。方法 应用西比灵治疗脑出血 36例 ,并与对照组 30例进行比较。结果 治疗组有效率为 86 % ,高于对照组 6 0 % (P <0 .0 5 ) ,西比灵治疗后神经功能缺损评分显著减少 ,与对照组比差异显著 (P <0 .0 1) ,且治疗组在治疗后血肿量及水肿面积均较对照组有明显缩小 (P <0 .0 1)。结论 提示西比灵早期使用对减轻脑出血后神经细胞的损害 ,减轻脑水肿均有明显的效果。
Objective To study the effect of xibinger on the treatment of edema around cerebral hemorrhage and further explore the mechanism of action of xibinger. Methods 36 cases of cerebral hemorrhage were treated with Sibelium, and compared with 30 cases of control group. Results The effective rate of the treatment group was 86%, which was higher than that of the control group (60%, P0.05). The neurological deficit score of the treatment group was significantly lower than that of the control group (P <0.01) ), And the treatment group in the treatment of hematoma volume and edema area were significantly reduced compared with the control group (P <0.01). The conclusions suggest that the early use of Sibelium has a significant effect on alleviating the damage of neurons after cerebral hemorrhage and relieving cerebral edema.