目的探讨重症肝炎中总胆红素水平、凝血酶原时间(PT)、并发症与其预后的关系。方法对该院1997~2001年收治的66例重症肝炎的预后进行回顾性分析。结果重症肝炎中总胆红素>400μmol/L,PT>25s的发生率分别为34.8%和39.3%,发生1个器官并发症1例,2个器官并发症10例,3个器官并发症6例,4个器官并发症6例,其死亡率依次升高。结论重症肝炎时出现总胆红素明显升高,凝血酶原时间显著延长,多器官/系统并发症出现时预后凶险。 Objective To investigate the relationship between total bilirubin level, prothrombin time (PT), complications and prognosis in severe hepatitis. Methods The prognosis of 66 cases of severe hepatitis treated in our hospital from 1997 to 2001 was analyzed retrospectively. Results The incidences of total bilirubin> 400μmol / L and PT> 25s in severe hepatitis were 34.8% and 39.3% respectively. One case had one organ complication, two had organ complication, and three had organ complications. Cases, 4 cases of organ complications in 6 cases, the mortality rate in turn. Conclusions Serum total bilirubin is significantly increased in severe hepatitis, prothrombin time is significantly prolonged, and multiple organ / systemic complications appear when the prognosis is dangerous.