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近年来由于成功地进行了人体白细胞抗原(HLA)的分型以及在人类组织配伍定型(Histocompatibility typing)方面取得了迅速进展,骨髓移植(BMT)正逐渐得到广泛的开展和运用,从而为严重再障和恶性血液病患者的长期生存展现了一个右望而可喜的途径。然而移植后所出现的一系列问题如排异反应、移植物抗宿主病(GVHD)、败血症、各种感染、间质性肺炎和其它肺部病变等,却严重影响了BMT的成功率,其中移植后的间质性肺炎及其后造成的呼吸衰竭可能成为移植后早期死亡的主要原因。因此,与BMT有关的肺部病变电不能不引起人们足够的重视。
In recent years, bone marrow transplantation (BMT) is gradually being widely used and applied due to the successful classification of human leukocyte antigen (HLA) and its rapid progress in human tissue Histocompatibility typing, The long-term survival of patients with Barrier and Hematologic Malignancies presents a right-wing and welcome route. However, a series of problems such as rejection, graft-versus-host disease (GVHD), sepsis, various infections, interstitial pneumonia and other pulmonary diseases after transplantation have seriously affected the success rate of BMT Interstitial pneumonitis after transplantation and subsequent respiratory failure may be the leading cause of early death after transplantation. Therefore, BMT-related lung lesions can not but cause enough attention.