糖尿病患者的糖尿病性肾病综合征预后恶劣。Schreiner随访了27例这类患者,其中18例(67％)死于肾病综合征出现后3个月到12年内。有肾功能衰竭与高血压时尤甚。作者报告一例28岁女性糖尿病患者的糖尿病性肾病综合征自然缓解达4年以上。患者因出现肾病综合征入院。10年前确诊有糖尿病。用甲苯磺丁脲治疗,偶因头痛而服阿司匹林。血压160/100。头皮与上下眼睑、手、足有浮肿。验尿有蛋白4~+,糖3~+,尿酮体阴性,镜下有许多脂肪滴与析光的脂肪小体。每高倍视野红细胞0～2,白细胞2～4,肾小管上皮细胞2～4及许多透明管型、颗粒管型和含有脂肪滴的管型。血清尿素氮24～30毫克/100毫升,胆固醇870～425毫克/100毫升。空腹与餐后两小时血糖均高。总蛋白5.1克/100毫升,白蛋白2.6克/100毫升。α_2-球蛋白1.1克/100毫升(正常0.3～0.9),γ-球蛋白0.4克/100毫升(正常0.5～1.5)。血清抗核抗体阴性。IgG 169毫克/100毫升(正常600 Diabetic patients with diabetic nephrotic syndrome have a poor prognosis. Schreiner followed 27 patients, 18 of whom (67%) died of nephrotic syndrome within 3 months to 12 years after their appearance. Especially when you have kidney failure and high blood pressure. The authors report a natural relief of diabetic nephrotic syndrome in a 28-year-old woman with diabetes for more than 4 years. Patients due to nephrotic syndrome admitted to hospital. Diabetes diagnosed 10 years ago. Tolbutamide treatment, even because of headache and aspirin. Blood pressure 160/100. Scalp with upper and lower eyelids, hands, feet full of edema. Urine protein 4 ~ +, sugar 3 ~ +, urine ketone body negative, there are many microscopic lipid droplets and the light of the fat body. Per high power red blood cells 0 to 2, leukocytes 2 to 4, renal tubular epithelial cells 2 to 4 and many transparent tube, granular tube and fat droplets containing the tube. Serum urea nitrogen 24 to 30 mg / 100 ml, cholesterol 870 ~ 425 mg / 100 ml. Fasting and postprandial blood glucose two hours are high. Total protein 5.1 g / 100 ml, albumin 2.6 g / 100 ml. α 2-globulin 1.1 g / 100 ml (normal 0.3 to 0.9), γ-globulin 0.4 g / 100 ml (normal 0.5 to 1.5). Serum anti-nuclear antibody negative. IgG 169 mg / 100 ml (normal 600