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本文报道了应用放射免疫分析方法检测30例健康成人、162例上胃肠道疾病病人空腹血清胃泌素浓度。其中食管癌10例;胃溃疡11例;十二指肠球部溃疡18例;萎缩性胃炎17例。结果表明,血清胃泌素浓度与正常对照组无明显差异。胃癌10例及浅表性胃炎96例,血清胃泌素值明显增高。讨论分析了上胃肠道疾病对血清胃泌素测定意义。
This article reported the use of radioimmunoassay to detect fasting serum gastrin concentrations in 30 healthy adults and 162 patients with upper gastrointestinal disorders. There were 10 cases of esophageal cancer, 11 cases of gastric ulcer, 18 cases of duodenal ulcer, and 17 cases of atrophic gastritis. The results showed that the serum gastrin concentration was not significantly different from the normal control group. In 10 cases of gastric cancer and 96 cases of superficial gastritis, serum gastrin values increased significantly. The significance of determination of serum gastrin in upper gastrointestinal diseases was discussed and analyzed.