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为了解既往使用过链、肼、柳的复治病人耐药情况,以期对选择合理的复治化疗方案有所助益;美国公卫服务处等机构自1961年9月起对国内22个医院住院病人4017名进行耐药性的调查研究、结果表明:总耐药率为41%,耐一药为18%,耐二药为14%,耐三药为9.1%。耐肼为36.8%,耐链、柳分别为19.2%及17.2%。本组病人中至少用过一期单药治疗者共1168例(29%),此类病人耐药率为60.9%,用过两药以上联合治疗者共4849例(71%),
In order to understand the past use of chain, hydrazine, willow retreatment patient resistance, with a view to the choice of reasonable rehabilitation chemotherapy regimen helpful; the United States Public Health Service and other institutions since September 1961 on the domestic 22 4017 hospital inpatients were investigated for drug resistance. The results showed that the overall resistance rate was 41%, resistance to one drug was 18%, resistance to two drugs was 14% and resistance to three drugs was 9.1%. Hydrazine resistance was 36.8%, resistance chain, willow were 19.2% and 17.2%. A total of 1168 patients (29%) were treated with at least one monotherapy in this group of patients. The drug resistance rate of these patients was 60.9%. A total of 4849 patients (71%) used two or more combination therapies,