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本文报道了广州地区622份健康人群脊髓灰质炎抗体水平。Ⅰ、Ⅱ、Ⅲ型抗体阳性率依次为95.82％、96.60％、90.10％,抗体几何平均滴度(GMT)依次为1:98.40、1:35.69、1:31.29,其中Ⅱ、Ⅲ型抗体GMT低,较Ⅰ型抗体GMT有显著性差异(P<0.01)。抗体阳性率和GMT两项指标在1～9岁年龄组最高。10岁以上人群脊髓灰质炎中和抗体随着年龄的增长而呈逐渐下降趋势。性别(男女之间)无显著性差异(P>0.05)。结果提示:本市儿童已获得较好的免疫屏障,但也存在着一定程度免疫裂隙。今后仍需进一步提高TOPV接种质量。
This article reports the polio antibody levels of 622 healthy people in Guangzhou. The positive rates of type I, type II and type III antibodies were 95.82%, 96.60% and 90.10%, respectively. The geometric mean titers of GMTs were 1: 98.40, 1: 35.69 and 1: 31.29, , Compared with the type I antibody GMT significant difference (P <0.01). Antibody positive rate and GMT two indicators in the highest age group 1 to 9 years. Polio neutralizing antibodies in the population over 10 years showed a gradual downward trend with age. Gender (between men and women) no significant difference (P> 0.05). The results suggest that: the city children have been better immune barrier, but there is also a certain degree of immune fissures. In the future still need to further improve TOPV vaccination quality.