“一点法”确定给药方案适用病人首次用药,而住院病人大都是入院前已使用氨茶硷治疗,因此无法应用一点法。同时病人需要及时治疗,这就要求有一个既不延误目前的治疗,又能为病人合理用药提供最佳方案的方法。我们知道给药次数n相当大时,血药浓度达到坪值(即稳态)时由下式给出: The “one-point method” confirms that the dosing regimen is applicable to the patient for the first time and inpatients are mostly treated with aminophylline before admission, so they can not apply the one-point method. At the same time, patients need timely treatment, which requires a method that will not delay the current treatment, but also provide the patient with the best program of rational drug use. We know that when the number of doses n is quite large, the plasma concentration reaches the plateau (ie steady state) and is given by: