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功能性消化不良(functional dyspepsia,FD)指一组表现为上腹部疼痛或烧灼感、餐后上腹饱胀和早饱感的症候群,其临床表现难以用器质性疾病解释,经检查血生化和内镜等排除这些症状的器质性疾病的一组临床综合征。FD患者占消化科门诊的20%~40%,我国人群患病率为10%~30%[1],机制不明。研究表明,发病主要与胃肠动力学障碍、胃感觉障碍有关[2,3],主要为进餐后胃底松弛障碍、胃电节律紊乱、胃窦无力和排空功能减慢、胃窦-幽门-十二指肠协调功能失常等,与精神心理因素、内脏感觉过敏、幽门螺杆菌感染、
Functional dyspepsia (FD) refers to a group of symptoms manifested as upper abdominal pain or burning sensation, postprandial abdominal fullness and early satiety syndrome, the clinical manifestations difficult to explain with organic diseases, after examination of blood biochemical And endoscopy and other organic diseases that exclude these symptoms of a group of clinical syndromes. FD patients account for 20% to 40% of gastroenterology clinics in China, the prevalence of 10% to 30% [1], the mechanism is unknown. Studies have shown that the incidence is mainly associated with gastrointestinal motility disorders and gastric sensory disturbances [2,3], mainly due to postprandial gastric fundus relaxation disorder, gastric electrical rhythm disorders, weakness of gastric antrum and emptying function, gastric antrum-pylorus - duodenal coordination dysfunction, etc., and mental and psychological factors, visceral hypersensitivity, Helicobacter pylori infection,