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目的通过回顾、对照、经验总结“海肤康”治疗创伤后皮肤缺损临床疗效,讨论适应证及优缺点。方法抽取我院2004年6月至2010年06月采用创伤后皮肤缺损130例,其中观察组(采用海肤康)治疗60例,对照组(手术植皮或皮瓣转移法)治疗70例,男性67例,女性63例。所有病例均在治愈后随访1~6个月,平均2.5个月。采用SPSS统计比较两组之间差异。结果采用海肤康治疗患者与手术治疗患者在表皮至深筋膜的缺损上治愈率上无明显差异,在深达骨质的缺损上治愈率显著低于对照组(P<0.05)。结论海肤康治疗创伤后皮肤缺损效果明确,如后减少疤痕的并发症需要进一步研究。
Objective By reviewing, comparing and summarizing the experience of treating skin lesions after trauma, the authors discuss the indications, advantages and disadvantages. Methods A total of 130 cases of skin defect after trauma were selected from June 2004 to June 2010 in our hospital. Among them, 60 cases were treated in the observation group (treated with seafloxacin) and 70 cases were treated in the control group (surgical skin grafting or flap transfer) 67 cases, 63 females. All cases were followed up for 1 to 6 months after the cure, with an average of 2.5 months. SPSS statistics were used to compare the differences between the two groups. Results There was no significant difference in the cure rate between the epidermis and the deep fascia on the patients treated with Haikuang and the surgical treatment. The cure rate on the deep bone defect was significantly lower than that in the control group (P <0.05). Conclusion Hai Kuang Kang treatment of post-traumatic skin defect clear effect, such as reducing the complications of scar need further study.