近年来,我们在研究益母草及其提取物活血化瘀作用的实验中,证明该药能改善大鼠异丙肾上腺素引起的心肌缺血,增加心肌营养血流量,改善肠系膜微循环障碍,以及体外抗ADP诱导的血小板聚集作用。为了进一步探索该药的活血化瘀机理,本文通过烫伤、冰水应激、和静脉注入ADP等不同方法,造成大鼠体内血小板聚集活性增高,对益母草在体抗血小板聚集作用作了观察。 In recent years, we have studied the effects of Motherwort and its extracts in promoting blood circulation and blood stasis, and have shown that the drug can improve isoprenaline-induced myocardial ischemia in rats, increase myocardial nutrient blood flow, improve mesenteric microcirculation, and in vitro Anti-ADP induced platelet aggregation. In order to further explore the mechanism of promoting blood circulation and stasis of the drug, the platelet aggregation activity in rats was increased by scald, ice-water stress, and intravenous injection of ADP. The antiplatelet aggregation of Herba Leonuri was observed.