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目的探讨胰腺转移性肿瘤的临床病理特点、诊治和预后。方法回顾性分析18例胰腺转移性肿瘤的临床病理资料,其中原发肿瘤为肺癌8例,胃癌2例,恶性纤维组织细胞瘤1例,甲状腺癌1例,黑色素瘤1例,卵巢癌1例,肾癌1例,食管癌1例,直肠癌1例,肝癌1例。胰腺转移性肿瘤无特异性临床症状。14例行CT或B超引导下细针穿刺活检,经细胞学检查证实;4例由术后组织病理学证实。在18例胰腺继发肿瘤中,单发14例,多发4例。结果CT平扫表现为胰腺低密度肿物,除肾癌胰腺转移灶表现为高血供,明显增强外,其余均表现为乏血管肿瘤,增强不明显。18例患者均行放化疗综合治疗,治疗后生存期8~38个月,平均生存期19个月。结论胰腺转移性肿瘤在临床上较为少见,无特异的临床症状和影像学表现。根据不同的原发肿瘤,选择合适的综合治疗模式,对于胰腺继发肿瘤的治疗和预后有重要的意义。
Objective To investigate the clinicopathological features, diagnosis, treatment and prognosis of pancreatic metastatic tumors. Methods The clinical data of 18 patients with metastatic pancreatic cancer were retrospectively analyzed. Among them, 8 were primary lung cancer, 2 gastric cancer, 1 malignant fibrous histiocytoma, 1 thyroid cancer, 1 melanoma, 1 ovarian cancer 1 kidney cancer, 1 esophageal cancer, 1 rectal cancer and 1 liver cancer. Pancreatic metastases have no specific clinical symptoms. Fourteen patients underwent CT or B-guided fine needle aspiration biopsy confirmed by cytology; 4 patients confirmed by postoperative histopathology. In 18 cases of pancreatic secondary tumors, 14 cases were single and 4 cases were multiple. Results CT scan showed low density of pancreatic tumors, in addition to renal cell carcinoma of the pancreas showed high blood supply, significantly enhanced, the remaining showed a lack of vascular tumors, the enhancement was not obvious. Eighteen patients underwent radiotherapy and chemotherapy combined treatment, survival after treatment for 8 to 38 months, the average survival of 19 months. Conclusions Pancreatic metastatic tumors are relatively rare in clinical practice, with no specific clinical symptoms and imaging findings. According to different primary tumors, selecting the appropriate comprehensive treatment mode is of great significance for the treatment and prognosis of secondary pancreatic tumors.