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目的探讨比较卡培他滨联合奥沙利铂与替吉奥联合奥沙利铂治疗进展期胃癌的效果。方法将本院收治的90例进展期胃癌患者随机分为观察组与参考组,各45例,分别给予两组患者卡培他滨联合奥沙利铂及替吉奥联合奥沙利铂治疗,观察两组患者近期治疗效果及并发症发生情况。结果观察组近期治疗总有效率为71.1%,参考组近期治疗总有效率为66.7%,差异无统计学意义(P>0.05);观察组患者并发症发生率与参考组比较差异无统计学意义(P>0.05)。结论卡培他滨联合奥沙利铂与替吉奥联合奥沙利铂治疗进展期胃癌近期效果显著,同时毒性反应较少,均可作为有效方案使用。
Objective To investigate the effect of capecitabine combined with oxaliplatin and tiotropium combined with oxaliplatin in the treatment of advanced gastric cancer. Methods 90 cases of advanced gastric cancer admitted to our hospital were randomly divided into observation group and reference group, 45 cases in each group. Capecitabine combined with oxaliplatin and tioguanide combined with oxaliplatin were given to two groups respectively. Observation of two groups of patients with short-term treatment and complications occurred. Results The total effective rate in the observation group was 71.1%, while the total effective rate in the reference group was 66.7% (P> 0.05). There was no significant difference in the complication rate between the observation group and the reference group (P> 0.05). Conclusion Capecitabine combined with oxaliplatin and tiotropium combined with oxaliplatin in the treatment of advanced gastric cancer has a significant effect in the near future, with less toxic reactions and can be used as an effective regimen.