对85例胰岛素瘤的诊断和治疗情况进行分析,认为Whipple三联征及胰岛素释放指数(IRI/G)>0.3可作为定性诊断的主要依据;对少数血糖>2.75mmol/L者,可结合饥饿试验进行诊断;胰岛素瘤多数直径较小,术前定位不易,术中探查及术中B超是发现肿瘤的主要手段,二者互为补充.对良性胰岛素瘤应力争行肿瘤摘除术,对肿瘤位于胰体尾,较大且深,或为多发肿瘤者,应行胰体尾切除术. The analysis of the diagnosis and treatment of 85 cases of insulinomas indicated that the Whipple triad and insulin release index (IRI/G)>0.3 can be used as the main basis for qualitative diagnosis; for a few blood glucose >2.75 mmol/L, it can be combined with the hunger test. Diagnosis; insulinomas, most of the smaller diameter, preoperative positioning is not easy, intraoperative exploration and intraoperative B-ultrasound is the main means of finding the tumor, the two are complementary to each other. On the benign insulinoma stress on the tumor removal surgery, on the tumor Pancreatic body and tail, large and deep, or multiple tumors should be pancreatic body resection.