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目的：研究微量元素水平在吸烟饮酒男性中的差异及对血压的影响。方法将104例男性分为四组，检测四组血中的微量元素水平的差异，并分析微量元素对血压的影响。结果2组、3组和4组铅含量显著地高于1组（P<0.05），2组、3组和4组的锌、钙和铁含量均显著地低于1组（P<0.05）。相关性分析表明，铅元素水平与收缩压、舒张压显著相关（P<0.05）。结论经常吸烟、饮酒会使有毒金属元素铅在体内积累，并造成有益元素锌、钙、铁的流失，导致血压异常。“,”Objective To study trace elements level differences in men who often smoke and drink, and its effect on blood pressure.Methods 104 patients were divided into four groups.The differences of trace element levels in the blood in four groups were detected,and the effect of trace elements on blood pressure was observed. Results Lead,of group 2,group 3 and group 4 was significantly higher than that of group 1 (P<0.05). Zinc, iron and calcium of group 2,group 3 and group 4 was significantly lower than that of group 1 (P<0.05).Correlation analysis showed that, Pb levels and systolic blood pressure, diastolic blood pressure was significantly related (P<0.05). Conclusion Regular smoking and drinking will cause lead accumulation in the body, lost zinc, calcium, iron, and lead to abnormal blood pressure.