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用国产肉毒毒素Ａ局部注射治疗偏侧睑及面肌痉挛６２例。应用Ｃｏｈｅｎ和Ａｌｂｅｒｔ表对病情进行评估。治疗后３天，５４例（８７．１％）患者病情较治疗前有显著改善，１个月复查时３８例（６１．２％）患者仍处于症状明显改善水平，２１例较治疗前痉挛分级减轻１级，３例与治疗前分级相同。３个月后随访有１５例（２４．２％）患者仍处于症状明显改善水平，３３例较治疗前痉挛分级减轻１级，１４例与治疗前分级相同。疗效平均维持９周左右，重复注射可再获疗效。１５例患者出现轻微的不良反应，不良反应在４～６周消失。观察表明，国产肉毒毒素Ａ治疗偏侧睑及面肌痉挛安全有效，简便易行，是目前临床首选的治疗方法。
Local injection of botulinum toxin A for the treatment of 62 cases of hemifacial spasm. The condition was evaluated using Cohen and Albert tables. Three days after treatment, 54 patients (87.1%) had significantly improved disease status compared with those before treatment, and 38 (61.2%) patients were still at significantly improved levels at one month’s review and 21 were better than pre-treatment spasms Reduce grade 1, 3 cases with the same classification before treatment. Fifteen patients (24.2%) were followed up at 3 months. The symptoms were still significantly improved in 33 patients. The grade of spasm was reduced by 1 grade in the 33 patients and the same as the grade in 14 patients before treatment. The effect of maintaining an average of about 9 weeks, repeat injection can be re-treated. 15 patients showed mild adverse reactions, adverse reactions disappeared in 4 to 6 weeks. Observations show that domestic botulinum toxin A is safe and effective in the treatment of hemiplegia and hemifacial spasm and is simple and easy to be applied. At present, it is the first choice of clinical treatment.