皮质层状坏死(cortical laminar necrosis,CLN),也称假层状坏死(pseudolaminar necrosis),可发生在不同年龄,见于多种原因造成的中枢神经系统氧和(或)糖的摄取障碍以及脑能量代谢的遗传或后天性缺陷。MRI的问世对 CLN有了更多的认识。本文对CLN的有关问题进行综述。 1 皮质层状坏死的组织病理学 CLN是一种特殊类型的皮质坏死,常常是广泛缺氧的结果,并非局部血管异常。在组织病理学上,CLN是一种 Cortical laminar necrosis (CLN), also known as pseudolaminar necrosis, can occur at various ages and is found in a variety of causes of central nervous system oxygen and / or glucose uptake disorders and brain energy Metabolic genetic or acquired defects. The advent of MRI CLN have more knowledge. This article summarizes the related issues of CLN. Histopathology of Corticobasal Necrosis CLN is a specific type of cortical necrosis that is often the result of extensive hypoxia and is not localized to vascular abnormalities. Histopathologically, CLN is one