为了进一步探讨肝胆舒康胶囊作用机理,以免疫性肝维维化模型大鼠为研究对象,测定肝纤维化有关生化血清学指标,进行分析研究。1 材料与方法 Wistar大鼠92只,雌雄各半,体重130～150g,由河南省中医药研究院实验动物中心提供。随机抽取10只作为正常组,用王保恩法将剩余大鼠致敏,15天后,将血清白蛋白抗体阳性者分成6组:实验空白对照组,秋水仙碱组,预防低剂量组与高剂量组,治疗低剂量组与高剂量组,进行尾静脉攻击注射人血白蛋白生理盐 In order to further explore the mechanism of action of Gandanshukang capsule, immuno-hepatic retinoviral model rats were used as the research object to determine the biochemical serological markers related to hepatic fibrosis and to analyze and study. 1 Materials and Methods 92 Wistar rats, male and female, weighing 130-150g, were provided by the Experimental Animal Center of Henan Institute of Traditional Chinese Medicine. Ten rats were randomly selected as the normal group and the remaining rats were sensitized with the Wang Baoen method. After 15 days, serum albumin-positive patients were divided into 6 groups: experimental control group, colchicine group, prevention low-dose group and high-dose group , treatment of low-dose group and high-dose group for tail vein attack injection of human serum albumin physiological salt