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目的了解上海市部分体检人群EB病毒壳抗原免疫球蛋白A抗体(EBVCA-Ig A)和早期抗原免疫球蛋白A抗体(EA-Ig A)的阳性率和鼻咽癌的发病率。方法对2013年在长海医院进行EBVCA-Ig A抗体和EBEA-Ig A抗体检测的健康体检人群的结果进行统计分析。结果 14 032名健康人群中EBVCA-Ig A抗体阳性175人,阳性率为1.25%,EBEAIg A抗体阳性125人,阳性率为0.89%,共同阳性者5人,发现鼻咽癌1人,人群检出率约为7.13/10万。EBVCA-Ig A和EA-Ig A抗体的阳性率与年龄无相关性。结论在上海开展EBVCA-Ig A和EA-Ig A抗体的联合检测进行鼻咽癌的早期筛查具有一定的临床意义。
Objective To investigate the positive rates of Epstein-Barr virus envelope antigen (EBVCA-Ig A) and early antigen immunoglobulin A antibody (EA-Ig A) in some physical examination population in Shanghai and the incidence of nasopharyngeal carcinoma. Methods Statistical analysis was performed on the results of the health examination population of EBVCA-Ig A and EBEA-Ig A antibodies tested in Changhai Hospital in 2013. Methods: Results The positive rate of EBVCA-Ig A antibody in 14 032 healthy people was 1.25%, the positive rate was 1.25%, the positive rate of EBEAIg A antibody was 125, the positive rate was 0.89%, 5 were positive and 1 was found in nasopharyngeal carcinoma. The rate is about 7.13 / 100,000. The positive rates of EBVCA-Ig A and EA-Ig A antibodies were not related to age. Conclusion The combination of EBVCA-Ig A and EA-Ig A antibodies in Shanghai early screening of nasopharyngeal carcinoma has some clinical significance.