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目的:探讨绒毛膜癌(绒癌)和侵蚀性葡萄胎患者临床多疗程化疗后的转归。方法:回顾性分析61例绒癌和侵蚀性葡萄胎患者化疗后临床疗效及毒副反应。结果:61例中,绒癌24例,近期缓解率为91.7%,侵蚀性葡萄胎37例,近期缓解率97.3%。耐药性恶性滋养细胞肿瘤患者10例,其中手术6例。结论:绒癌和侵蚀性葡萄胎经化疗保留子宫是可行的,化疗效果可靠。
Objective: To investigate the prognosis of patients with choriocarcinoma and aggressive hydatidiform mole after multi-course chemotherapy. Methods: The clinical efficacy and side effects of chemotherapy in 61 cases of choriocarcinoma and invasive hydatidiform mole were retrospectively analyzed. Results: In 61 cases, choriocarcinoma was found in 24 cases, the recent remission rate was 91.7%, and the erosive mole was 37 cases, the recent remission rate was 97.3%. Ten patients with drug-resistant malignant trophoblastic tumor, including 6 cases of surgery. Conclusion: Chemoembolization of choriocarcinoma and invasive hydatidiform mole is feasible and the chemotherapy effect is reliable.