Puzzle out the regulation mechanism of PI4KⅡα activity

来源 :中国科学:生命科学英文版 | 被引量 : 0次 | 上传用户:gz_firefox
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
<正>Phosphatidylinositol 4-kinaseⅡα(PI4KⅡα),the most abundant PI4K in mammalian cells,is best known for its essential role in providing the substrate for phosphatidylinositol 3-kinase(PI3K),an important kinase for phospholipid signaling.PI4KIIα also
其他文献
Although microRNAs(miRNAs) have been intensively studied in cardiac fibrosis,their roles in drug-mediated anti-fibrotic therapy are still unknown.Previously,Pio
We documented the number, morphology, and distribution of intermuscular bones in five fishes of different ploidy: Carassius auratus (Abbr.WCC, 2n=100), Carassiu
Archaea, along with Bacteria and Eukarya, are the three domains of life. In all living cells, chromatin proteins serve a crucial role in maintaining the integri
Electron microscopy(EM) should be used in the front line for detection of agents in emergencies and bioterrorism,on accounts of its speed and accuracy.However,t
Marine-derived Bacillus strains have been proved to be a very promising source for natural product leads.However,transformation of environmental strains is much
Clearance of apoptotic neutrophils by macrophages is important for both the successful resolution of acute inflammation and homeostasis.However,the dynamic proc
<正>Acquired immunodeficiency syndrome(AIDS)was first reported in 1981[1].Five healthy young men suddenly presented with opportunistic pneumonia caused by Pneum
<正>Structural and functional alterations of synaptic connections underlay experience-dependent neuronal plasticity and are crucial for many brain functions,inc
Beauvericin, a cyclohexadepsipeptide-possessing natural product with synergistic antifungal, insecticidal, and cytotoxic activities. We isolated and characteriz
<正>The structural information of functionally important macromolecular assemblies is a key to molecular biology and is of great interest to structural biologis