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研究36例地方性克汀病患者的多形式脑诱发电位发现,全部病人的BAEPS异常,其中15例进行ECochG检查,表现为电平坦或N_1后延。33例的SSEPS检查,9例异常,异常率为27.27%。34例VEPS检查,8例异常,异常率为25.5%。研究结果表明:地方性克汀病人的听觉损害部位在耳蜗内,而不在蜗后听神经及脑干内的传导束上。碘和甲状腺激素缺乏引起的脑皮层萎缩及视觉传导通路某部位损害可能是SSEPS、VEPS异常的病理基础。
To investigate the pleomorphic brain evoked potentials in 36 patients with endemic cretinism, BAEPS abnormalities were found in all patients. ECochG examination was performed in 15 of them, showing a flattened or N_1-delayed. 33 cases of SSEPS examination, 9 cases of abnormalities, the abnormal rate was 27.27%. 34 cases of VEPS examination, 8 cases of abnormalities, the abnormal rate was 25.5%. The results show that: local cretinism in patients with auditory damage within the cochlea, but not in the cochlear auditory nerve and brainstem conduction beam. Iodine and thyroid hormone deficiency caused by cortical atrophy and damage to a part of the visual conduction pathway may be the pathological basis of SSEPS, VEPS abnormalities.