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通过培养人黄体细胞检查了促性腺激素释放激素(GnRH)及其强有力的促效剂[(imBzl)-D-His~6-Pro~9-NEt]-GnRH 对基础的和人绒毛膜促性腺激素(HCG)兴奋的孕酮(P),雄烯二酮(Δ~(?)A),雌二醇(E_2)产生的可能直接效应。作者从10名无妇科内分泌疾患行子宫全切除术的妇女中获得黄体组织。选择早期或中期黄体期的黄体,(晚期黄体在试管内对 HCG 或其他兴奋剂如PGE_2不发生孕酮分泌反应)。将黄体打碎成单细胞悬液,浓度为2.5～5.0×10~6活细胞/ml。在细胞悬液中分别不加任何物质(对照),或加 HCG,
The effect of GnRH and its potent agonist [(imBzl) -D-His ~ 6-Pro ~ 9-NEt] -GnRH on basal and human chorionic progenitors was examined by culturing human luteal cells Progesterone (P), progesterone (Δ ~ (?) A) and estradiol (E2) excited by gonadotropin (HCG) may have direct effects. The authors obtained luteal tissue from 10 women who underwent total hysterectomy without gynecological endocrine disorders. Select the early or mid luteal phase of the corpus luteum, (late corpus luteum HCG or other stimulants such as PGE 2 progesterone secretion test tube). Broken corpus luteum into a single cell suspension at a concentration of 2.5 to 5.0 × 10 6 viable cells / ml. In the cell suspension without any substance (control), or add HCG,