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目的 综述蛋白质组学在医药研究中的应用 ,为医疗及药物开发提供参考。方法 根据国内外文献 ,结合笔者应用蛋白质组学对药物合成途径的研究 ,介绍研究蛋白质组学的意义以及蛋白质组学研究的主要手段 ,重点为蛋白质组学在疾病机制研究 ,药物靶点筛选以及药物开发方面的潜力 ,并分析了蛋白质组学的发展及技术局限性。结果和结论 蛋白质组学的研究方兴未艾 ,已经在生命科学的研究中显示出巨大的潜力 ,蛋白质组学将成为药物开发必不可少的工具之一
Objective To summarize the application of proteomics in medical research and provide references for medical and drug development. Methods Based on the literature both at home and abroad, combining with the application of proteomics to the study of drug synthesis pathways, this paper introduces the significance of proteomics research and the main means of proteomics research, focusing on the research of proteomics in disease mechanism, drug target screening and Potential for drug development, and analysis of proteomics development and technical limitations. RESULTS AND CONCLUSION Proteomics research is in the ascendant and has shown great potential in life science research, and proteomics will become one of the essential tools for drug development