本文用Draize 法皮肤致敏试验证明,百菌清是一种化学致敏物,皮肤接触可引起接触性皮炎;淋巴细胞被动转移实验结果提示皮肤反应属近发型变态反应性质。给致敏动物吸入百菌清粉尘,可导致变应性间质性肺炎、甚至造成死亡。因此,生产和使用百菌清的作业场所,必须采取有效防尘和个人皮肤防护措施。 In this paper, Draize method skin sensitization test proved that chlorothalonil is a chemical sensitizer, skin contact can cause contact dermatitis; lymphocyte passive transfer test results suggest that the skin reaction is a near-allergic nature. Inhalation of chlorothalonil dust to sensitized animals can cause allergic interstitial pneumonia and even death. Therefore, the production and use of chlorothalonil workplace must be effective dust and personal skin protection measures.