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目的:通过两焦点、三焦点对山羊下颌骨缺损进行牵张,比较两种牵张成骨方式的新骨成骨量。方法:将8只成年山羊随机分成两组,每组4只,分别采用两焦点和三焦点牵张成骨术进行骨缺损修复。牵张结束后固定8周,处死动物取牵张区新生骨组织标本进行X线检查、组织学检查、骨密度分析。结果:两实验组牵张区新骨生长的质无明显区别,在量的比较上,三焦点组X线检查、组织学检查、骨密度测定的结果均好于两焦点组,骨密度测定分析结果有统计学意义(P<0.05)。结论:三焦点牵张成骨在大面积颌骨缺损的修复中新骨的成骨量好于两焦点牵张成骨组。
OBJECTIVE: To investigate the mandibular defects of goats by means of two focal points and three focal points, and to compare the bone remodeling of two new types of distraction osteogenesis. Methods: Eight adult goats were randomly divided into two groups with 4 rats in each group. Bifocal and triple focal distraction osteogenesis were performed respectively to repair the bone defects. After the stretch was fixed for 8 weeks, the animals were sacrificed to take distracted bone tissue samples for X-ray examination, histological examination, bone mineral density analysis. Results: There was no significant difference in the quality of new bone growth between the two experimental groups. In terms of the quantitative comparison, the results of X-ray examination, histological examination and bone mineral density measurement of triple-focus group were better than those of the two focal groups. The result was statistically significant (P <0.05). Conclusion: The triple-focus distraction osteogenesis of new bone in the repair of large-scale jaw defects is better than the two-focus distraction osteogenesis group.