环孢素是一强有力的免疫抑制剂,国内应用多为进口,价格昂贵,目前国内已合成。环孢素它可以选择性抑制辅助性T细胞和细胞毒性T细胞的前体细胞的分化、增殖,对抑制性T细胞的增殖无影响。它阻断了活化的T_H细胞产生和释放白细胞介素Ⅱ导致T细胞介导的炎症反应减弱,Tc细胞的特异性杀伤作用受到影响从而能有效的降低细胞介导的同种异体移植排斥反应的发生,延长移植物宿主的存活。它可促进B淋巴细胞的增殖,故环孢素可影响 Cyclosporine is a potent immunosuppressant, domestic applications are mostly imported, expensive, the current domestic synthesis. Cyclosporine can selectively inhibit the differentiation and proliferation of helper T cells and precursor cells of cytotoxic T cells and has no effect on the proliferation of inhibitory T cells. It blocks the production and release of interleukin-2 from activated T-H cells, which leads to the decrease of T cell-mediated inflammatory reaction and the specific killing effect of Tc cells, which can effectively reduce the cell-mediated rejection of allograft Occur, prolong the survival of the graft host. It can promote the proliferation of B lymphocytes, it can affect cyclosporine