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采用综合累积暴露指数（ＩＣＥ），将工人接触ＣＳ２浓度和接触期限结合起来定量评价暴露强度，并检测尿中２－硫代噻唑烷－４－羧酸（ＴＴＣＡ）和儿茶酚胺类神经递质代谢产物的含量。结果显示：接触组尿中ＴＴＣＡ增高，存在剂量－效应关系；高接触组高香草酸（ＨＶＡ）和香草扁桃酸（ＶＭＡ）排泄减少。这两种儿茶酚胺代谢产物与ＣＳ２浓度及工龄虽未显示有显著意义的相关，但与ＩＣＥ及ＴＴＣＡ之间却呈现统计学上的相关关系，表明长期接触ＣＳ２对儿茶酚胺类神经递质代谢有一定的干扰作用。
Exposure to 2-thio-thiazolidine-4-carboxylic acid (TTCA) and catecholamine neurotransmitter metabolites in urine were quantitatively evaluated using a composite cumulative exposure index (ICE) in combination with exposure to CS2 and contact duration. Content. The results showed that there was a dose-effect relationship between TTCA in urine and the excretion of HVA and VMA in high exposure group. The two catecholamine metabolites did not show significant correlation with CS2 concentration and length of service, but showed a statistically significant relationship with ICE and TTCA, indicating that long-term exposure to CS2 had some effect on catecholamine neurotransmitter metabolism Interference effect.