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目的探析婚前体检人群感染HBV的情况。方法入选我院2013年1月~2013年12月婚前体检者9000人,应用酶联免疫吸附试验及免疫金标记法检测乙肝表面抗原、谷丙转氨酶(ALT)。结果婚检者9000例检出180例HBsAg阳性,其中男104例,女76例,阳性率0.02%,性别之间检测具有统计学差异(P>0.05);对180例HBsAg阳性者检测HBV血清标记情况,其中大三阳67例,小三阳85例,抗-HBC+HBsAg阳性10例,HBsAg阳性者18例;180例HBsAg阳性者检测肝功能ALT异常者4例,阳性率2.22%。结论婚前进行感染HBV筛查,有助于进行免疫预防及降低疾病感染率,确保优生。
Objective To investigate the prevalence of HBV infection in premarital health examination population. Methods Ninety-five pre-marital medical exams were enrolled in our hospital from January 2013 to December 2013. ELISA and immunogold labeling were used to detect hepatitis B surface antigen and alanine aminotransferase (ALT). Results Among the 9,000 cases of pregnancy, 180 cases of HBsAg positive were detected, including 104 males and 76 females, the positive rate was 0.02%. There was a significant difference between the sexes (P> 0.05) Among them, 67 cases of Sanyang and 85 cases of Sanyang were positive in 10 cases of anti-HBC + HBsAg and 18 cases of HBsAg positive; 180 cases of HBsAg positive were detected in 4 cases with abnormal liver function ALT, the positive rate was 2.22%. Conclusions HBV infection screening before marriage is helpful for immunoprophylaxis and reduction of disease infection rate to ensure eugenics.