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为了对照性研究应用西地那非 (Sildenafil,ViagraTM)和育亨宾治疗男子阴茎勃起功能障碍 (ED)的效果。把 2 34例ED(器质性 41 % ,心理性 46 % ,混合性 1 3% )随机双盲分为两组 ,西地那非组 1 34例 ,用西地那非 5 0～ 1 0 0mg ,性交前 6 0分钟口服 ,每天一次 ,连服 2天后 ,改为 2～ 3天服一次 ,连用 4～ 1 2周。育亨宾组 1 0 0例 ,用育亨宾 (Yohimbine) 5 .4～ 1 0 .8mg ,每天服 3次 ,连用 4～ 1 2周。结果表明西地那非组口服西地那非 5 0～ 1 0 0mg后 ,有效率为 6 1 .1 9～ 79.1 0 % ,育亨宾组的有效率为 40 % ,两组疗效经统计学处理有显著性差别 (P <0 .0 1 )。本资料显示西地那非治疗各种原因的ED是安全有效的 ,副作用少而轻 ,可以长期治疗 ,相比之下育亨宾的效果较差
To compare the effects of sildenafil (ViagraTM) and yohimbine in the treatment of men with erectile dysfunction (ED) for comparative purposes. Two hundred and seventy-two cases of ED (organic 41%, psychological 46%, mixed 13%) were randomly divided into two groups. One hundred and thirty-three patients in the sildenafil group were treated with sildenafil 50-100 0mg, 60 minutes before sexual intercourse oral, once daily, and even served 2 days later, changed to 2 to 3 days a time, once every 4 to 12 weeks. Yohimbine group 100 cases, Yohimbine (Yohimbine) 5.4 ~ 1.08 mg, 3 times a day, once every 4 to 12 weeks. The results showed that sildenafil group after oral sildenafil 50 ~ 100mg, the effective rate was 61.91 ~ 79.1 0%, yohengbin effective rate was 40%, the two groups were statistically significant There was a significant difference in treatment (P <0.01). This data shows that sildenafil for the treatment of various causes of ED is safe and effective, with few side effects and light, long-term treatment, in contrast yohimbine less effective