胃肠道间质瘤(gastrointestinal stromal tumor,GIST)是消化道常见的间叶源性肿瘤,长期以来一直被认为是消化道平滑肌(肉)瘤或(恶性)神经鞘膜瘤。1983年,Mazur和Clark运用电镜和免疫组化重新评估胃间叶源性肿瘤的发生,提出了GIST的概念[1]。近年来研究表明,GIST是胃肠道最常见 Gastrointestinal stromal tumor (GIST), a common mesenchymal tumor in the digestive tract, has long been considered as gastrointestinal smooth muscle (or myoma) or (malignant) nerve sheath tumor. In 1983, Mazur and Clark reassessed the incidence of gastric mesenchymal tumors using electron microscopy and immunohistochemistry. The concept of GIST was proposed [1]. In recent years, studies have shown that GIST is the most common gastrointestinal tract