生物钟系统可分为输入、振荡器、输出。输入指光、温、化学物质等可以重拨生物钟相位的环境因子。输出指生物钟所控制的过程、行为等。而振荡器则为核心,产生自我持续的反馈机制。研究发现负反馈调节、翻译和翻译后加工决定着生物钟周期的长短。粗糙脉孢霉ＦＲＱ和果蝇ＰＥＲ的 Biological clock system can be divided into input, oscillator, output. Enter the environmental factor that indicates the phase of the biological clock, such as light, temperature, chemicals, etc. Output refers to the biological clock controlled by the process, behavior and so on. The oscillator is the core, resulting in self-sustained feedback mechanism. The study found that negative feedback regulation, translation and post-translation processing determine the length of the biological clock cycle. Neurospora crassa FRQ and Drosophila PER