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目的分析艾滋病感染者(患者)其配偶(固定性伴)受感染的影响因素,为防止艾滋病的二代传播提供参考建议。方法采用现况研究了解四川省3地区的艾滋病感染者(患者)及其配偶(固定性伴)HIV的感染现状,使用非条件logistic回归模型分析HIV异性性传播的影响因素。结果单因素logistic回归分析显示,艾滋病感染者(患者)其配偶(固定性伴)受感染的影响因素有:艾滋病感染者(患者)接受艾滋病药物治疗情况(OR=0.498,P=0.027)、性行为频率(OR=4.065,P=0.047)、配偶(固定性伴)的吸毒情况(OR=2.195,P=0.021)、配偶(固定性伴)认为自身感染HIV的可能性(OR=0.089,P=0.000);多因素logistic回归分析显示,配偶认为自己感染HIV的风险(OR=0.077,P=0.000)和每周1次及以上的性行为频率(OR=5.148,P=0.045)是影响艾滋病感染者(患者)其配偶(固定性伴)受感染的主要影响因素。结论调查地区艾滋病感染者(患者)及其配偶(固定性伴)间的性行为频率以及配偶认为自己感染HIV的可能性是影响HIV在异性固定性伴间传播的主要因素。因此,加强异性固定性伴间的性行为干预是防止艾滋病二代传播的重要途径。
Objective To analyze the influencing factors of infection of spouse (fixed partner) of HIV-infected patients (patients), and to provide reference for preventing the second-generation transmission of AIDS. Methods The status of HIV infection in 3 HIV / AIDS patients (spouses) and their spouses (sex partners) in 3 areas of Sichuan Province was studied. The non-conditional logistic regression model was used to analyze the influencing factors of HIV heterosexual transmission. Results The univariate logistic regression analysis showed that the influencing factors of the infection of AIDS patients (patients) with their spouses (fixed partners) were AIDS patients (patients) receiving AIDS drugs (OR = 0.498, P = 0.027), sex (OR = 2.065, P = 0.047), spouse (regular partner) drug use (OR = 2.195, P = 0.021) and spouse (regular partner) = 0.000). Multivariate logistic regression analysis showed that the risk of spouse being infected with HIV (OR = 0.077, P = 0.000) and the frequency of sexual behavior once or more weekly (OR = 5.148, P = 0.045) Infected (patients) their spouses (fixed partners) infection of the main factors. Conclusions The frequency of sexual behavior among HIV-infected persons (patients) and their spouses (sex partners) in the surveyed area and the probability that the spouse considers themselves HIV-infected are the main factors that influence the transmission of HIV among heterosexual partners. Therefore, to strengthen sexual intercourse between heterosexual intercourse intervention is an important way to prevent the spread of second-generation AIDS.