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目的探讨医院新生儿科发生医院感染的高危因素,调查某医院新生儿科抗菌药物使用情况。方法抽取2011年6月至12月新生儿住院病历426例做回顾性分析。结果住院新生儿的医院感染高危因素分别为:男性、早产儿、低出生体重儿、吸入综合征、新生儿窒息、羊水污染、重症监护、气管插管、长时间住院、预防应用抗菌药物。抗菌药物使用率较高、细菌培养率和药敏试验率达不到要求、预防用药过多。结论该院新生儿使用抗菌药物尚存在不合理现象,应加强培训和管理,督促临床医生合理应用抗菌药物。
Objective To investigate the risk factors of nosocomial infection in neonatology in hospitals and to investigate the use of antimicrobial drugs in neonates in a hospital. Methods A retrospective analysis of 426 neonates with in-patient records from June to December in 2011 was conducted. Results High risk factors of nosocomial neonatal hospital infection were: male, premature infant, low birth weight infants, inhalation syndrome, neonatal asphyxia, amniotic fluid contamination, intensive care, endotracheal intubation, prolonged hospitalization, prevention and treatment of antimicrobial agents. Antibacterial drug use rate is higher, the rate of bacterial culture and drug susceptibility test failed to meet the requirements, prevention of medication too much. Conclusion There is an unreasonable phenomenon in the use of antimicrobial drugs in neonates in this hospital. Training and management should be strengthened to urge clinicians to use antimicrobial drugs reasonably.