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通过对120例支气管哮喘妇女于月经周期利用组织胺为激发剂进行非特异性激发试验,以激发浓度PC_(20)-PEF、激发阈值PD_(20)-PEF、24小时波动率为观察指标,观察月经前期(月经前1周)、月经期、月经期后(月经后1周)的变化,发现支气管哮喘妇女月经期间PC_(20)-PEF、PD_(20)-PEF均低于月经前期及月经期后,月经前期低于月经期后,24小时PEF于月经期间波动率最大,其中有36例(30%)临床上有哮喘症状出现,通过观察说明妇女月经期间气道反应性增强,月经周期和支气管哮喘有密切关系。
120 cases of bronchial asthma women in the menstrual cycle using histamine as a stimulant for non-specific stimulation test to stimulate the concentration of PC_ (20) -PEF, threshold PD_ (20) -PEF, 24-hour volatility was observed The changes of PC_ (20) -PEF and PD_ (20) -PEF in women with bronchial asthma during menstruation were lower than that in menopause and menstruation After the period, the premenstrual period is lower than the menstrual period, the 24-hour PEF during the menstrual period the most volatile, of which 36 cases (30%) clinically asthma symptoms, through observation shows that women during menstruation increased airway responsiveness, menstrual cycle And bronchial asthma are closely related.