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肾小球硬化是由各种原因所致的肾小球损伤或病变的共同结局。肾小球细胞外基质（ｅｘｔｒａｃｕｌａｒｍａｔｒｉｘ，ＥＣＭ）积聚是引起肾小球硬化的重要病理基础。正常生理条件下，肾小球ＥＣＭ的合成与降解呈现相对平衡状态，这对维持肾小球的正常结构和功能起着重要作...
Glomerulosclerosis is a common outcome of glomerular lesions or lesions caused by a variety of causes. Accumulation of glomerular extracellular matrix (extracularmatrix, ECM) is an important pathological basis for glomerulosclerosis. Under normal physiological conditions, synthesis and degradation of glomerular ECM showed a relatively balanced state, which plays an important role in maintaining the normal structure and function of glomerular ...