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测定了72例食管癌病人外周血和癌组织中T细胞亚群、自然杀伤细胞活性(NK)、抗体依赖细胞毒活性(ADCC)、淋巴细胞转化率(LT)、免疫球蛋白和补体C3。结果表明,食管癌病人外周血及癌组织中T细胞亚群及TH/TS明显改变,NK、ADCC、LT有程度不同的降低;外周血中IgG、IgA、C3均明显升高以及癌组织中IgG直接荧光染色阳性与肿瘤转移密切相关。
The T cell subsets, natural killer cell activity (NK), antibody-dependent cytotoxicity (ADCC), lymphocyte transformation rate (LT), immunoglobulin, and complement C3 in peripheral blood and cancer tissues were determined in 72 patients with esophageal cancer. The results showed that T lymphocyte subsets and TH/TS in peripheral blood and cancer tissues of esophageal cancer patients were significantly changed, NK, ADCC, and LT were decreased to varying degrees; IgG, IgA, and C3 levels in peripheral blood were significantly increased and cancer tissues were detected. Positive IgG direct fluorescent staining is closely related to tumor metastasis.